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Mitochondrial Reactive Oxygen Species Are Activated by mGluR5 through IP(3) and Activate ERK and PKA to Increase Excitability of Amygdala Neurons and Pain Behavior

Reactive oxygen species (ROS) such as superoxide are emerging as important signaling molecules in physiological plasticity but also in peripheral and spinal cord pain pathology. Underlying mechanisms and pain-related ROS signaling in the brain remain to be determined. Neuroplasticity in the amygdala...

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Detalhes bibliográficos
Main Authors: Li, Zhen, Ji, Guangchen, Neugebauer, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073477/
https://ncbi.nlm.nih.gov/pubmed/21248136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5387-10.2011
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