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Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol
G protein-coupled receptor kinase 2 (GRK2) is a pharmaceutical target for the treatment of cardiovascular diseases such as congestive heart failure, myocardial infarction, and hypertension. To better understand how nanomolar inhibition and selectivity for GRK2 might be achieved, we have determined t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073382/ https://ncbi.nlm.nih.gov/pubmed/20128603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9017515 |
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