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Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After Fontan Operation: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

BACKGROUND: Children and young adults with single ventricle physiology have abnormal exercise capacity after Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow for improved cardiac filling and improved exercise capacity. METHODS AND RESULTS: This study wa...

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Detalhes bibliográficos
Main Authors: Goldberg, David J., French, Benjamin, McBride, Michael G., Marino, Bradley S., Mirarchi, Nicole, Hanna, Brian D., Wernovsky, Gil, Paridon, Stephen M., Rychik, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073351/
https://ncbi.nlm.nih.gov/pubmed/21382896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.981746
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