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A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes.
Hammerhead ribozymes targeted against two unrelated RNA substrates have been prepared. For each substrate, four ribozymes, differing in their hybridising arm length and composition (DNA or RNA), have been synthesised and kinetically characterised. The presence of DNA in the hybridising arms had litt...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1995
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3928 |
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