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Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

Manganese porphyrin-linker-triple-helix-forming oligonucleotide molecules were prepared and their ability to cleave in vitro a double-stranded DNA target present in the HIV-1 genome was studied. The nature of the linker is a determining factor of the cleavage efficiency. Cleavage yields as high as 8...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Bigey, P, Pratviel, G, Meunier, B
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1995
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307307/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3894
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