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Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

Manganese porphyrin-linker-triple-helix-forming oligonucleotide molecules were prepared and their ability to cleave in vitro a double-stranded DNA target present in the HIV-1 genome was studied. The nature of the linker is a determining factor of the cleavage efficiency. Cleavage yields as high as 8...

詳細記述

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書誌詳細
主要な著者: Bigey, P, Pratviel, G, Meunier, B
フォーマット: Artigo
言語:Inglês
出版事項: 1995
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC307307/
https://ncbi.nlm.nih.gov/pubmed/7479033
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