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Pentatricopeptide Repeat Proteins Stimulate mRNA Adenylation/Uridylation to Activate Mitochondrial Translation in Trypanosomes

The majority of trypanosomal mitochondrial pre-mRNAs undergo massive uridine insertion/deletion editing which creates open reading frames. Although the pre-editing addition of short 3′ A-tails is known to stabilize transcripts during and after the editing, the processing event committing the fully-e...

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Main Authors: Aphasizheva, Inna, Maslov, Dmitri, Wang, Xiaorong, Huang, Lan, Aphasizhev, Ruslan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073060/
https://ncbi.nlm.nih.gov/pubmed/21474072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.021
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