Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1.

The essential role of urokinase-type plasminogen activator (uPA) in tumor invasion and metastasis stresses the necessity of a fine-tuned cellular control over its expression. It has been shown that changes in uPA directly correlate with changes in cell invasiveness. We examined the role of Rel-relat...

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Publicat a:Nucleic Acids Res
Autors principals: Reuning, U, Wilhelm, O, Nishiguchi, T, Guerrini, L, Blasi, F, Graeff, H, Schmitt, M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1995
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3887
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