The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

BACKGROUND: The protein tyrosine phosphatase nonreceptor type 2 (PTPN22) has been established as a type 1 diabetes susceptibility gene. A recent study found the C1858T variant of this gene to be associated with lower residual fasting C-peptide levels and poorer glycemic control in patients with type...

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Main Authors: Nielsen, Lotte B, Pörksen, Sven, Andersen, Marie Louise M, Fredheim, Siri, Svensson, Jannet, Hougaard, Philip, Vanelli, Maurizio, Åman, Jan, Mortensen, Henrik B, Hansen, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072937/
https://ncbi.nlm.nih.gov/pubmed/21429197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-41
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