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The rate of hemolysis in sickle cell disease correlates with the quantity of active von Willebrand factor in the plasma
Vaso-occlusion, hemolysis, and oxidative stress are hallmarks of sickle cell disease (SCD). This pathology is accompanied by systemic endothelial activation, rendering the endothelium more adhesive for blood cells, including sickle erythrocytes. Activated endothelial cells display or secrete several...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072883/ https://ncbi.nlm.nih.gov/pubmed/21300978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-302539 |
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