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Immunization with Live and Dead Chlamydia muridarum Induces Different Levels of Protective Immunity in a Murine Genital Tract Model: Correlation with MHC Class II Peptide Presentation and Multifunctional Th1 Cells

Mice that were intranasally vaccinated with live or dead Chlamydia muridarum with or without CpG-containing oligodeoxynucleotide 1862 elicited widely disparate levels of protective immunity to genital tract challenge. We found that the frequency of multifunctional T cells coexpressing IFN-γ and TNF-...

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Detalhes bibliográficos
Main Authors: Yu, Hong, Karunakaran, Karuna P., Kelly, Isabelle, Shen, Caixia, Jiang, Xiaozhou, Foster, Leonard J., Brunham, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072838/
https://ncbi.nlm.nih.gov/pubmed/21296978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002952
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