Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast

The phosphorylation and dephosphorylation of proteins by kinases and phosphatases constitute an essential regulatory network in eukaryotic cells. This network supports the flow of information from sensors through signaling systems to effector molecules, and ultimately drives the phenotype and functi...

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Main Authors: Bodenmiller, Bernd, Wanka, Stefanie, Kraft, Claudine, Urban, Jörg, Campbell, David, Pedrioli, Patrick G., Gerrits, Bertran, Picotti, Paola, Lam, Henry, Vitek, Olga, Brusniak, Mi-Youn, Roschitzki, Bernd, Zhang, Chao, Shokat, Kevan M., Schlapbach, Ralph, Colman-Lerner, Alejandro, Nolan, Garry P., Nesvizhskii, Alexey I., Peter, Matthias, Loewith, Robbie, von Mering, Christian, Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072779/
https://ncbi.nlm.nih.gov/pubmed/21177495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001182
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