DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism

Pancreatic cancer is an exceptionally aggressive disease in great need of more effective therapeutic options. Epithelial-mesenchymal transition (EMT) plays a key role in cancer invasion and metastasis and there is a gain of stem cell properties during EMT. Here we report increased expression of the...

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Auteurs principaux: Sureban, Sripathi M., May, Randal, Lightfoot, Stan A., Hoskins, Aimee B., Lerner, Megan, Brackett, Daniel J., Postier, Russell G., Ramanujam, Rama, Mohammed, Altaf, Rao, Chinthalapally V., Wyche, James H., Anant, Shrikant, Houchen, Courtney W.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072762/
https://ncbi.nlm.nih.gov/pubmed/21285251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2738
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