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Selective Reduction of Graft-versus-Host Disease-Mediating Human T Cells by Ex Vivo Treatment with Soluble Fas Ligand

Previous work done in our laboratory, using mouse models, showed that soluble Fas ligand (sFasL) can efficiently delete donor anti-host T cells during their activation against irradiated host cells in MLCs. In the mouse models, this ex vivo sFasL treatment abrogated graft-vs-host disease (GVHD) whil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bohana-Kashtan, Osnat, Morisot, Sebastien, Hildreth, Richard, Brayton, Cory, Levitsky, Hyam I., Civin, Curt I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072680/
https://ncbi.nlm.nih.gov/pubmed/19535642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800561
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