Deoxypodophyllotoxin Induces a Th1 Response and Enhances the Antitumor Efficacy of a Dendritic Cell-based Vaccine

BACKGROUND: Dendritic cell (DC)-based vaccines are currently being evaluated as a novel strategy for tumor vaccination and immunotherapy. However, inducing long-term regression in established tumor-implanted mice is difficult. Here, we show that deoxypohophyllotoxin (DPT) induces maturation and acti...

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Detalhes bibliográficos
Main Authors: Lee, Jun Sik, Kim, Dae Hyun, Lee, Chang-Min, Ha, Tae Kwun, Noh, Kyung Tae, Park, Jin Wook, Heo, Deok Rim, Son, Kwang Hee, Jung, In Duk, Lee, Eun Kyung, Shin, Yong Kyoo, Ahn, Soon-Cheol, Park, Yeong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072678/
https://ncbi.nlm.nih.gov/pubmed/21494377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2011.11.1.79
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