Long Signaling Cascades Tend to Attenuate Retroactivity

Signaling pathways consisting of phosphorylation/dephosphorylation cycles with no explicit feedback allow signals to propagate not only from upstream to downstream but also from downstream to upstream due to retroactivity at the interconnection between phosphorylation/dephosphorylation cycles. Howev...

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Autors principals: Ossareh, Hamid R., Ventura, Alejandra C., Merajver, Sofia D., Del Vecchio, Domitilla
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
Matèries:
Biological Systems and Multicellular Dynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072653/
https://ncbi.nlm.nih.gov/pubmed/21463574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.014
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