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The Relationship of Oxygen Transport and Cardiac Index for the Prevention of Sickle Cell Crises

The formation of deoxyhemoglobin S (deoxy-Hb S) polymers is the key triggering event for the complex pathophysiologic manifestations of sickle cell anemia (SCA). This polymer formation is associated with a marked right-shifted oxyhemoglobin dissociation curve (decreased affinity, increased P(50)), w...

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Detalhes bibliográficos
Main Authors: Farrell, Kevin, Dent, Leon, Nguyen, Minh Ly, Buchowski, Maciej, Bhatt, Ananta, Aguinaga, Maria del Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072584/
https://ncbi.nlm.nih.gov/pubmed/21141287
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