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Connectedness of PPI network neighborhoods identifies regulatory hub proteins
Motivation: With the growing availability of high-throughput protein–protein interaction (PPI) data, it has become possible to consider how a protein's local or global network characteristics predict its function. Results: We introduce a graph-theoretic approach that identifies key regulatory p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072558/ https://ncbi.nlm.nih.gov/pubmed/21367871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr099 |
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