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Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps.

The remarkable processivity of cellular replicative DNA polymerases derive their tight grip to DNA from a ring-shaped protein that encircles DNA and tethers the polymerase to the chromosome. The crystal structures of prototypical 'sliding clamps' of prokaryotes (beta subunit) and eukaryote...

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Dettagli Bibliografici
Autori principali: Kelman, Z, O'Donnell, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC307255/
https://ncbi.nlm.nih.gov/pubmed/7478986
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