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Fingerprint-Based Structure Retrieval Using Electron Density

We present a computational approach that can quickly search a large protein structural database to identify structures that fit a given electron density, such as determined by cryo-electron microscopy. We use geometric invariants (fingerprints) constructed using 3D Zernike moments to describe the el...

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Bibliographic Details
Main Authors: Yin, Shuangye, Dokholyan, Nikolay V.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072439/
https://ncbi.nlm.nih.gov/pubmed/21287628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22941
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