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Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides.
Short oligonucleotides that can bind to adjacent sites on target mRNA sequences are designed and evaluated for their binding affinity and biological activity. Sequence-specific binding of short tandem oligonucleotides is compared with a full-length single oligonucleotide (21mer) that binds to the sa...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1995
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307240/ https://ncbi.nlm.nih.gov/pubmed/7567472 |
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