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Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies

Genome-wide association studies (GWAS) examine a large number of markers across the genome to identify associations between genetic variants and disease. Most published studies examine only single markers, which may be less informative than considering multiple markers and multiple genes jointly bec...

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Autors principals: Chen, Min, Cho, Judy, Zhao, Hongyu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072362/
https://ncbi.nlm.nih.gov/pubmed/21490723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001353
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