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Convergent DNA synthesis: a non-enzymatic dimerization approach to circular oligodeoxynucleotides.

We report a novel convergent approach to the construction of circular DNA oligonucleotides from two smaller linear precursors. Circular DNAs 34-74 nucleotides (nt) in size are constructed non-enzymatically in a single step from two half-length oligomers. A DNA template is used to assemble the consti...

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Bibliographic Details
Main Authors: Rubin, E, Rumney, S, Wang, S, Kool, E T
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307236/
https://ncbi.nlm.nih.gov/pubmed/7567468
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