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Singlet oxygen mediated DNA degradation by copper nanoparticles: potential towards cytotoxic effect on cancer cells

The DNA degradation potential and anti-cancer activities of copper nanoparticles of 4-5 nm size are reported. A dose dependent degradation of isolated DNA molecules by copper nanoparticles through generation of singlet oxygen was observed. Singlet oxygen scavengers such as sodium azide and Tris [hyd...

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Detalles Bibliográficos
Main Authors: Jose, Gregor P, Santra, Subhankar, Mandal, Swadhin K, Sengupta, Tapas K
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072310/
https://ncbi.nlm.nih.gov/pubmed/21439072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-9-9
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