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Presynaptic CLC-3 Determines Quantal Size of Inhibitory Transmission in the Hippocampus

The absence of the chloride channel CLC-3 in Clcn3(−/−) mice results in hippocampal degeneration with a distinct temporal-spatial sequence reminiscent of neuronal loss in temporal lobe epilepsy. We examined how the loss of CLC-3 might impact GABAergic synaptic transmission in the hippocampus. An ele...

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Bibliografiske detaljer
Main Authors: Riazanski, Vladimir, Deriy, Ludmila V., Shevchenko, Pavel D., Le, Brandy, Gomez, Erwin A., Nelson, Deborah J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072292/
https://ncbi.nlm.nih.gov/pubmed/21378974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2775
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