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The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1

The cullin4A-RING E3 ubiquitin ligase (CRL4) is a multisubunit protein complex, comprising cullin4A (CUL4), RING H2 finger protein (RBX1) and DNA damage-binding protein 1 (DDB1). Proteins that recruit specific targets to CRL4 for ubiquitination (ubiquitylation), bind the DDB1 adaptor protein via WD4...

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Detalhes bibliográficos
Main Authors: Ahn, Jinwoo, Novince, Zach, Concel, Jason, Byeon, Chang-Hyeock, Makhov, Alexander M., Byeon, In-Ja L., Zhang, Peijun, Gronenborn, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072279/
https://ncbi.nlm.nih.gov/pubmed/21226479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101749s
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