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Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury

Endotoxin induced acute lung injury is a commonly used model. However, the effect of a priming dose of endotoxin on lung fluid balance has not been well studied. We hypothesized that endotoxin induced acute lung injury in mice would be enhanced under a priming condition. Mice were intratracheally (I...

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Detalhes bibliográficos
Main Authors: Lee, Joyce S., Su, Xiao, Rackley, Craig, Matthay, Michael A., Gupta, Naveen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072226/
https://ncbi.nlm.nih.gov/pubmed/21157927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.21244
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