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Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle

AIMS/HYPOTHESIS: Homozygous staggerer (sg/sg) mice, which have decreased and dysfunctional Rorα (also known as Rora) expression in all tissues, display a lean and dyslipidaemic phenotype. They are also resistant to (high fat) diet-induced obesity. We explored whether retinoic acid receptor-related o...

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Главные авторы: Lau, P., Fitzsimmons, R. L., Pearen, M. A., Watt, M. J., Muscat, G. E. O.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071927/
https://ncbi.nlm.nih.gov/pubmed/21279323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2046-3
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