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EFFECTS OF MEMBRANE CHOLESTEROL DEPLETION AND GPI-ANCHORED PROTEIN REDUCTION ON OSTEOBLASTIC MECHANOTRANSDUCTION

We previously demonstrated that oscillatory fluid flow activates MC3T3-E1 osteoblastic cell calcium signaling pathways via a mechanism involving ATP releases and P2Y(2) puringeric receptors. However, the molecular mechanisms by which fluid flow initiates cellular responses are still unclear. Accumul...

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Detalhes bibliográficos
Main Authors: Xing, Yanghui, Gu, Yan, Xu, Li-Chong, Siedlecki, Christopher A., Donahue, Henry J., You, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071886/
https://ncbi.nlm.nih.gov/pubmed/21660958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22579
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