Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures

BACKGROUND: Insulin-like growth factor 1 receptor (IGF1R) targeted therapies have resulted in responses in a small number of patients with advanced metastatic Ewing's sarcoma. We performed morphoproteomic profiling to better understand response/resistance mechanisms of Ewing's sarcoma to I...

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Detalhes bibliográficos
Main Authors: Subbiah, Vivek, Naing, Aung, Brown, Robert E., Chen, Helen, Doyle, Laurence, LoRusso, Patricia, Benjamin, Robert, Anderson, Pete, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071831/
https://ncbi.nlm.nih.gov/pubmed/21494688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018424
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