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Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

UFM1 is a member of the ubiquitin like protein family. While the enzymatic cascade of UFM1 conjugation has been elucidated in recent years, the biological function remains largely unknown. In this report we demonstrate that the recently identified C20orf116 [1], which we name UFM1-binding protein 1...

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Detalhes bibliográficos
Main Authors: Lemaire, Katleen, Moura, Rodrigo F., Granvik, Mikaela, Igoillo-Esteve, Mariana, Hohmeier, Hans E., Hendrickx, Nico, Newgard, Christopher B., Waelkens, Etienne, Cnop, Miriam, Schuit, Frans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071830/
https://ncbi.nlm.nih.gov/pubmed/21494687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018517
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