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Recombinant Complement Receptor 2 Radiolabeled with [(99m)Tc(CO)(3)](+) : A Potential New Radiopharmaceutical for Imaging Activated Complement
We describe the design and synthesis of a new Tc-99m labeled bioconjugate for imaging activated complement, based on Short Consensus Repeats 1 and 2 of Complement Receptor 2 (CR2), the binding domain for C3d. To avoid non specific modification of CR2 and the potential for modifying lysine residues c...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071809/ https://ncbi.nlm.nih.gov/pubmed/21494666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018275 |
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