Recombinant Complement Receptor 2 Radiolabeled with [(99m)Tc(CO)(3)](+) : A Potential New Radiopharmaceutical for Imaging Activated Complement

We describe the design and synthesis of a new Tc-99m labeled bioconjugate for imaging activated complement, based on Short Consensus Repeats 1 and 2 of Complement Receptor 2 (CR2), the binding domain for C3d. To avoid non specific modification of CR2 and the potential for modifying lysine residues c...

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Detalhes bibliográficos
Main Authors: Badar, Adam, DeFreitas, Sarah, McDonnell, James M., Yahya, Norhakim, Thakor, David, Razavi, Reza, Smith, Richard, Sacks, Steven, Mullen, Gregory E. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071809/
https://ncbi.nlm.nih.gov/pubmed/21494666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018275
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