The Septic Milieu Triggers Expression of Spliced Tissue Factor mRNA in Human Platelets

BACKGROUND: Activated platelets have previously-unrecognized mechanisms of post-transcriptional gene expression that may influence hemostasis and inflammation. A novel pathway involves splicing of pre-mRNAs in resting platelets to mature, translatable mRNAs in response to cellular activation. OBJECT...

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Bibliografiska uppgifter
Huvudupphovsmän: Rondina, M. T., Schwertz, H., Harris, E. S., Kraemer, B. F., Campbell, R. A., Mackman, N., Grissom, C. K., Weyrich, A. S., Zimmerman, G. A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071458/
https://ncbi.nlm.nih.gov/pubmed/21255247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04208.x
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