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Targeting pyrimidine single strands by triplex formation: structural optimization of binding.

Recent reports describe a new strategy for the binding of single-stranded pyrimidine sequences by triple helix formation. In this approach, a double-length purine-rich oligonucleotide binds a target strand, folding back to form an antiparallel pur.pur.pyr triple helix. We now describe a series of st...

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Detalles Bibliográficos
Autores principales: Vo, T, Wang, S, Kool, E T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC307133/
https://ncbi.nlm.nih.gov/pubmed/7544889
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