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Ephrin reverse signaling controls palate fusion via a PI3 kinase-dependent mechanism

Secondary palate fusion requires adhesion and epithelial to mesenchymal transition (EMT) of the epithelial layers on opposing palatal shelves. This EMT requires transforming growth factor β3 (TGFβ3), and its failure results in cleft palate. Ephrins, and their receptors, the Ephs, are responsible for...

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Detalhes bibliográficos
Main Authors: Miguel, Symone San, Serrano, Maria J., Sachar, Ashneet, Henkemeyer, Mark, Svoboda, Kathy K. H., Benson, M. Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071159/
https://ncbi.nlm.nih.gov/pubmed/21246652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22546
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