High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial

(See the editorial commentary by Carr, on pages 751–2.) Background. 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) exhibit antiviral activity against human immunodeficiency virus type 1 (HIV-1) in vitro and may modulate the immune response to HIV infection. Studies evaluating...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ganesan, Anuradha, Crum-Cianflone, Nancy, Higgins, Jeanette, Qin, Jing, Rehm, Catherine, Metcalf, Julia, Brandt, Carolyn, Vita, Jean, Decker, Catherine F., Sklar, Peter, Bavaro, Mary, Tasker, Sybil, Follmann, Dean, Maldarelli, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071124/
https://ncbi.nlm.nih.gov/pubmed/21325137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq115
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