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Neoplastic Transformation Induced by the gep Oncogenes Involves the Scaffold Protein JNK-Interacting Leucine Zipper Protein

The activated mutants of the α-subunits of G proteins G(12) and G(13) have been designated as the gep oncogenes owing to their ability to stimulate diverse oncogenic signaling pathways that lead to neoplastic transformation of fibroblast cell lines and tumorigenesis in nude mice models. Studies from...

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Bibliografische gegevens
Hoofdauteurs: Kashef, Kimia, Radhakrishnan, Rangasudhagar, Lee, Clement M, Reddy, E Premkumar, Dhanasekaran, Danny N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press Inc. 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071084/
https://ncbi.nlm.nih.gov/pubmed/21472140
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