Characterization of the Colloidal Properties, In vitro Antifungal Activity, Antileishmanial Activity and Toxicity in Mice of a Distigmasterylhemisuccinoyl-glycerophosphocholine Liposome-Intercalated Amphotericin B

1,2-Distigmasterylhemisuccinoyl-sn-glycero-3-phosphocholine (DSHemsPC) is a new lipid in which two molecules of stigmasterol (an inexpensive plant sterol) are covalently linked via a succinic acid to glycerophosphocholine. Since amphotericin B (AmB) interacts with sterols, we postulated that DSHemsP...

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Bibliografiska uppgifter
Huvudupphovsmän: Iman, Maryam, Huang, Zhaohua, Szoka, Francis C., Jaafari, Mahmoud R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071037/
https://ncbi.nlm.nih.gov/pubmed/21277963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.01.044
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