The trinucleotide repeat sequence d(GTC)15 adopts a hairpin conformation.

The structure of a single-stranded (ss) oligonucleotide containing (GTC)15 [ss(GTC)15] was examined. As a control, parallel studies were performed with ss(CTG)15, an oligonucleotide that forms a hairpin. Electrophoretic mobility, KMnO4 oxidation and P1 nuclease studies demonstrate that, similar to s...

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Bibliographic Details
Main Authors: Yu, A, Dill, J, Wirth, S S, Huang, G, Lee, V H, Haworth, I S, Mitas, M
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307095/
https://ncbi.nlm.nih.gov/pubmed/7651831
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