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Integration of Genotypic and Phenotypic Screening Reveals Molecular Mediators of Melanoma-Stromal Interaction

Tumor-endothelium interactions are critical for tumor survival and metastasis. Melanomas can rapidly metastasize early in tumor progression, but the dependence of this aggressive behavior on tumor-stromal interaction is poorly understood. To probe the mechanisms involved, we developed a heterotypic...

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Autors principals: Stine, Megan J., Wang, C. Joanne, Moriarty, Whei F., Ryu, Byungwoo, Cheong, Raymond, Westra, William H., Levchenko, Andre, Alani, Rhoda M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070809/
https://ncbi.nlm.nih.gov/pubmed/21324919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1875
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