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Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

The molecular identification of tumor antigens initially catalyzed substantial enthusiasm for the development of tumor antigen-based vaccines for the treatment of cancer. However, numerous vaccine approaches in melanoma and other cancers have yielded a low rate of clinical response, despite frequent...

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Detalhes bibliográficos
Main Authors: Gajewski, Thomas F., Fuertes, Mercedes, Spaapen, Robbert, Zheng, Yan, Kline, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070788/
https://ncbi.nlm.nih.gov/pubmed/21185705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.11.013
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