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Pitiprolamide, a Proline-Rich Dolastatin 16 Analogue from the Marine Cyanobacterium Lyngbya majuscula from Guam

An unusual cyclic depsipeptide, pitiprolamide (1), was isolated from the marine cyanobacterium Lyngbya majuscula collected at Piti Bomb Holes, Guam. The structure was deduced using NMR, MS, X-ray crystallography and enantioselective HPLC-MS techniques. Remarkably, proline represents half of the resi...

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Main Authors: Montaser, Rana, Abboud, Khalil A., Paul, Valerie J., Luesch, Hendrik
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070785/
https://ncbi.nlm.nih.gov/pubmed/21138309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np1006839
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