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Pitiprolamide, a Proline-Rich Dolastatin 16 Analogue from the Marine Cyanobacterium Lyngbya majuscula from Guam

An unusual cyclic depsipeptide, pitiprolamide (1), was isolated from the marine cyanobacterium Lyngbya majuscula collected at Piti Bomb Holes, Guam. The structure was deduced using NMR, MS, X-ray crystallography and enantioselective HPLC-MS techniques. Remarkably, proline represents half of the resi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Montaser, Rana, Abboud, Khalil A., Paul, Valerie J., Luesch, Hendrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070785/
https://ncbi.nlm.nih.gov/pubmed/21138309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np1006839
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