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Toll-like receptor driven B cell activation in the induction of systemic autoimmunity

Studies over the past decade have demonstrated a key role for pattern recognition receptors in the activation of autoreactive B cells. Self reactive B cells that manage to escape negative selection often express relatively low affinity receptors for self antigens (ignorant B cells), and can only be...

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Detalhes bibliográficos
Main Authors: Green, Nathaniel M., Marshak-Rothstein, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070769/
https://ncbi.nlm.nih.gov/pubmed/21306913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.01.016
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