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Monitoring response and resistance to treatment in chronic myeloid leukemia

Chronic myeloid leukemia (cml) results from expression of the constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. Imatinib, a tyrosine kinase inhibitor (tki), is highly effective in the treatment of cml. However, some patients treated with imatinib will fail to respond, will respond su...

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Bibliografiske detaljer
Main Authors: Assouline, S., Lipton, J.H.
Format: Artigo
Sprog:Inglês
Udgivet: Multimed Inc. 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070714/
https://ncbi.nlm.nih.gov/pubmed/21505592
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