Correlation of SHOX2 Gene Amplification and DNA Methylation in Lung Cancer Tumors

BACKGROUND: DNA methylation in the SHOX2 locus was previously used to reliably detect lung cancer in a group of critical controls, including 'cytologically negative' samples with no visible tumor cell content, at a high specificity based on the analysis of bronchial lavage samples. This st...

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Autori principali: Schneider, Katja U, Dietrich, Dimo, Fleischhacker, Michael, Leschber, Gunda, Merk, Johannes, Schäper, Frank, Stapert, Henk R, Vossenaar, Erik R, Weickmann, Sabine, Liebenberg, Volker, Kneip, Christoph, Seegebarth, Anke, Erdogan, Fikret, Rappold, Gudrun, Schmidt, Bernd
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070682/
https://ncbi.nlm.nih.gov/pubmed/21426551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-102
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