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Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution
BACKGROUND: Cationic antimicrobial peptides (CAMPs) are well recognized to be promising as novel antimicrobial and antitumor agents. To obtain novel skeletons of CAMPs, we propose a simple strategy using acid-amide substitution (i.e. Glu→Gln, Asp→Asn) to confer net positive charge to natural non-ant...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070621/ https://ncbi.nlm.nih.gov/pubmed/21418660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-0711-10-11 |
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