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Oligonucleotides containing fluorescent 2'-deoxyisoinosine: solid-phase synthesis and duplex stability.

The fluorescent nucleoside 2'-deoxyisoinosine (2, isoId) has been incorporated into oligonucleotides. For this purpose the phosphonate 3a and the phosphoramidite 3b, as well as the polymer-linked 3d, have been synthesized and oligonucleotides were prepared by P(III) solid-phase chemistry. One o...

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Autors principals: Seela, F, Chen, Y
Format: Artigo
Idioma:Inglês
Publicat: 1995
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC307057/
https://ncbi.nlm.nih.gov/pubmed/7630728
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