Discoidin Domain Receptor 1: Isoform Expression and Potential Functions in Cirrhotic Human Liver

Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that binds and is activated by collagens. Transcriptional profiling of cirrhosis in human liver using a DNA array and quantitative PCR detected elevated mRNA expression of DDR1 compared with that in nondiseased liver. The present study...

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Bibliographic Details
Main Authors: Song, Sunmi, Shackel, Nicholas A., Wang, Xin M., Ajami, Katerina, McCaughan, Geoffrey W., Gorrell, Mark D.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2011
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070552/
https://ncbi.nlm.nih.gov/pubmed/21356365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.068
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