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Dendritic cell vaccination against ovarian cancer – tipping the Treg/Th17 balance to therapeutic advantage?
The pathology of ovarian cancer is characterized by profound immunosuppression in the tumor microenvironment. Mechanisms that contribute to the immunosuppressed state include tumor infiltration by regulatory T cells (Treg), expression of B7-H1 (PDL-1), which can promote T cell anergy and apoptosis t...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070487/ https://ncbi.nlm.nih.gov/pubmed/21271951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.554812 |
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