Antibodies Elicited by Inactivated Propionibacterium acnes-Based Vaccines Exert Protective Immunity and Attenuate the IL-8 Production in Human Sebocytes: Relevance to Therapy for Acne Vulgaris

Propionibacterium acnes is a key pathogen involved in the progression of inflammation in acne vulgaris. We examined whether vaccination against P. acnes suppressed P. acnes-induced skin inflammation. Inactivation of P. acnes with heat was employed to create a P. acnes-based vaccine. Intranasal immun...

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Bibliographic Details
Main Authors: Nakatsuji, Teruaki, Liu, Yu-Tsueng, Huang, Cheng-Po, Gallo, Richard L., Huang, Chun-Ming
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070419/
https://ncbi.nlm.nih.gov/pubmed/18463682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.117
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